Perna mussels are a good source of protein, minerals, and chondroitin sulfates. Along with Glucosamine, MSM and Perna canaliculus, GLYCO-FLEX® II contains other ingredients such as Manganese and N,N Dimethylglycine (DMG). Vetri-Science holds 5 U.S. patents on DMG which demonstrates the multiple benefits that this ingredient can provide for the health and well being of the dog. The Perna canaliculus used in GLYCO-FLEX® II is produced by freeze-drying the entire mussel (excluding the shell) of the Perna Mussel from New Zealand . Formula: Each Chewable Tablet Contains: Glyco-Flex® II, Glucosamine HCl 750 mg, Perna canaliculus (Green-Lipped) Mussel 600 mg, Methylsulfonylmethane 500 mg, Brewers Yeast 181 mg, Stearic Acid 152 mg, N, N Dimethylglycine HCl 100 mg, Manganese Amino Acid Chelate 67 mg (contains 10 mg elemental Manganese), Silicon Dioxide 54 mg, Smoke Flavor 24 mg Suggested Use: Initial: (4-6 Weeks) Up to 30 lbs: 1/2 tablet daily per 30 lbs body weight 31-60 lbs: 1 tablet daily 61-100 lbs: 2 tablets daily 101 lbs and over: 2 1/2 tablets daily After initial period, the number of tablets per day may be reduced to a maintenance level. Maintenance: Up to 30 lbs: 1/2 tablet every other day per 30 lbs body weight 31-60 lbs: 1/2 tablet daily 61-100 lbs: 1 tablet daily 101 lbs and over: 1 1/2 tablets daily If giving more than one tablet, divide between AM and PM.