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Product Description: Denosyl and Marin support the liver through differing actions and may be used individually or in combination. Denamarin is one such patented combination liver supplement for dogs and cats containing both pure and stabilized S-Adenosylmethionine (SAMe) and silybin-phosphatidylcholine complex. Both SAMe and silybin have been shown to markedly increase levels of antioxidants formed when cats and dogs metabolize it. Silybin also helps with liver cell regeneration and enhances levels of glutathione, the liver’s major “detoxifying” agent. Denamarin has no known side-effects. Directions for Use: Tablets should be given on an empty stomach at least one hour before a meal for optimal absorption ( overnight fast preferred). For owners who find it difficult to administer tablets to their pets, Denamarin tablets may be disguised in a small bite of food. The number of tablets administered may be gradually reduced, or increased, at any time at the recommendation of your veterinarian. Storage: Store in a cool dry place. Keep tablets in original blister pack until used. Tablets are sensitive to moisture and extreme heat and should not be split or crumbled.